METAFECTENE? PRO是針對哺乳動物細胞的新一代轉(zhuǎn)染試劑。采用毒性優(yōu)化專利技術(shù)（TOP技術(shù)），Biontex成功地降低了轉(zhuǎn)染試劑對細胞的毒性，并顯著提高DNA進入細胞的效率。除了能加強細胞的轉(zhuǎn)染效率之外，METAFECTENE? PRO的另一個主要特點是提高細胞內(nèi)基因的表達。

注：TOP技術(shù)(Toxicity Optimization Module)

毒性最小化是現(xiàn)代轉(zhuǎn)染試劑達到最高效率和廣泛應(yīng)用性的首要前提條件。TOP技術(shù)的基本準則是模擬物質(zhì)天然結(jié)構(gòu)，加強生物降解能力，提高細胞耐受性。另外，通過物理化學(xué)修飾，降低脂質(zhì)復(fù)合體的穩(wěn)定性，從而促進DNA在細胞質(zhì)的釋放。

Suitable for DNA, mRNA, siRNA and miRNA transfection as well as cotransfection of DNA and RNA

Suitable for stable and transient transfection

Suitable for adherend and suspension cells

Minimized toxic effects

Optimized transfection rates

Free from serum inhibition

Comprehensive library of user reports

Wide range of references in specialist literature

METAFECTENE? PRO is a liposome based transfection reagent consisting of a mixture of polycationic and neutral lipids. It is an advanced product based on METAFECTENE?. Structural changes of the comprising cationic lipids results in higher efficiency and lower toxicity.

METAFECTENE? PRO is part of a temporal development series of transfection reagents from Biontex, which includes in particular the following reagents: METAFECTENE? < METAFECTENE? PRO < K2? Transfection System < K4? Transfection System. With the development degree the probability of a successful transfection increases (see also General Selection Aid).

Low cytotoxicity and lack of serum inhibition allow for a wide range of applications. METAFECTENE? PRO is suitable for transient and stable transfection of mammalian cell lines and primary cells with DNA (plasmids, bacmids), RNA (mRNA, miRNA and siRNA) and modified nucleic acids (antisense oligonucleotides). Areas of application are particularly the production of proteins, antibodies, and viruses (e.g. adenoviruses, AAV, lentiviruses), cotransfections of different nucleic acids, genome editing (e.g. CRISPR/Cas9, CRISPR/Cpf1) and gene silencing (gene knockdown).

默瑞(上海)生物科技有限公司，作為專業(yè)的生命科學(xué)產(chǎn)品推廣與服務(wù)商，以“創(chuàng)新，專業(yè)，共贏”的理念，不斷強化服務(wù)體系，提升客戶體驗，結(jié)合國內(nèi)外優(yōu)質(zhì)產(chǎn)品提供高標準完整解決方案，幫助科研客戶和生物技術(shù)企業(yè)高效創(chuàng)新，加速轉(zhuǎn)化，創(chuàng)造更多優(yōu)質(zhì)產(chǎn)品，提升社會福祉，實現(xiàn)多方共贏。

默瑞生物創(chuàng)立以來,已經(jīng)陸續(xù)導(dǎo)入TwistDx,博日

Jackson,izon,Biontex,Immunostep,101Bio,enzymatics,AATBioquest,KAPABIOSYSTEMS,BioDynami,Echelon,ChromoTek,Nanocs,Biotechrabbit,LeeBiosolutions, magtivio等優(yōu)質(zhì)國際品牌，逐步培育成為專業(yè)用戶的首選。